Skip to content
  • About
  • Contact
  • Contribute
  • Book
  • Careers
  • Podcast
  • Recommended
  • Speaking
  • All
  • Physician
  • Practice
  • Policy
  • Finance
  • Conditions
  • .edu
  • Patient
  • Meds
  • Tech
  • Social
  • Video
    • All
    • Physician
    • Practice
    • Policy
    • Finance
    • Conditions
    • .edu
    • Patient
    • Meds
    • Tech
    • Social
    • Video
    • About
    • Contact
    • Contribute
    • Book
    • Careers
    • Podcast
    • Recommended
    • Speaking

What John Snow and cholera tell us about the COVID pandemic

Brian Elliott, MD
Conditions
May 13, 2020
626 Shares
Share
Tweet
Share

It’s hard to imagine that someone could die from diarrhea. If you live in America today, you’ve likely never heard of anyone with cholera, and certainly never of anyone dying from diarrhea. Yet, in the middle of the nineteenth century, it was fairly commonplace. Medicine just wasn’t advanced at the time. Amputating limbs of fully-conscious human beings was only recently falling out of favor with the discovery of ether as an anesthetic in 1847. Louis Pasteur had yet to publish his germ theory that would revolutionize the understanding of infectious diseases.

In between these two landmark discoveries, at the West End of London in a town called Soho, was the cholera epidemic of 1854. Dozens of Londoners were dying from unrelenting diarrhea, profound dehydration, and electrolyte disturbances. Most people of the era pointed to the miasmatic theory of disease as the cause, meaning that bad smells caused the disease. It may sound silly now, but think about explaining germ theory to someone who has never heard it. Would you go with invisible creatures or tiny, tiny bugs as the cause of disease?

Ultimately the hero that would help put an end to the outbreak was John Snow – and before you ask – no, not the “winter is coming” Jon Snow. He had his doubts about the miasmatic theory and set out to find the true cause of the epidemic, mapping every person infected and searching for the common denominator. His results were striking. Nearly every death was clustered around a single water pump – the Broad Street pump. When he explored the outliers from this common denominator, he found that almost all persons not living directly near the Broad Street pump were still getting their water there due to preference.

So John Snow set out to prove his point with a plea to public officials, armed with his theory of water contamination and a map of cases clustered around the Broad Street pump that would go down in history as a revolutionary epidemiologic discovery. He was largely met with doubt and skepticism. Though, due to his persistence, officials would reluctantly order that the pump handle be removed from the Broad Street pump. Simple as that, the cholera outbreak in Soho came to a trickle.

Fast-forwarding to today’s pandemic, the rules still apply. Social intervention is, by far, the most powerful tool in mitigating the spread of infectious disease outbreaks. Cholera expedited medical advances, such as the invention of oral rehydration therapy and intravenous fluids. But these advancements were of greater benefit to posterity than the epidemic at hand. Today, rapid advancements in telemedicine, vaccination programs, and oxygenation therapies in acute respiratory distress syndrome will be tremendously helpful to our posterity. However, they will not stop, or even slow, a pandemic. This fact is largely because good science takes time, and social interventions do not.

After the epidemic in Soho came to a halt and John Snow essentially proved his theory correct, you can imagine what happened next. The people of Soho hosted a large parade in his honor, hoisted a statue to commemorate his revolutionary advancement in epidemiology, and gave him thousands of dollars as a thank you. Except they did none of those things. In fact, after the epidemic slowed, John Snow was met with nearly more doubt than before. Most people clenched tightly to their miasmatic theory. Even an appointed Committee of Scientific Inquiry who looked into the epidemic would attribute it to miasma. After only a brief period, public officials even replaced the Broad Street pump handle, and it would remain there, distributing water contaminated by a nearby cesspool for years.

In epidemiology, it’s difficult to prove your point, especially if the conclusion would incite change or overturn conventional theories. Either the intervention doesn’t work, the disease continues to spread, and people doubt you; or the intervention works, the disease stops, and people doubt you. The latter is often rationalized that the initial fears were overblown, and the intervention wasn’t necessary in the first place.

Similar viewpoints are being brought up in the COVID pandemic. Many states are seeing infection rates vastly below initial predictions, making the illogical conclusion that social interventions weren’t necessary in the first place. In fact, many are calling for an abrupt halt to social distancing and protesting for such changes. Instead of clutching to bad smells this time, it’s conspiracy theories and hidden agendas. It will likely be the case that, just like John Snow, epidemiologists and public policy will likely go woefully under-appreciated during this time period. Judging from the cholera outbreak, it will only take a century or two for people to come around.

Brian Elliott is an internal medicine resident.

Image credit: Shutterstock.com

Prev

To improve care, health systems must adopt diversity and inclusion

May 13, 2020 Kevin 0
…
Next

In the aftermath of COVID-19, plaintiff attorneys will have a field day

May 13, 2020 Kevin 2
…

Tagged as: COVID, Infectious Disease

Post navigation

< Previous Post
To improve care, health systems must adopt diversity and inclusion
Next Post >
In the aftermath of COVID-19, plaintiff attorneys will have a field day

More by Brian Elliott, MD

  • The controversial origin of the Hippocratic oath

    Brian Elliott, MD
  • Questioning medical traditions for the sake of patient care

    Brian Elliott, MD

Related Posts

  • The social determinants of health during the COVID-19 pandemic

    Heather Thompson Buum, MD
  • A response to unemployment during the COVID pandemic: Medicare for all   

    Mallika Sabharwal, MD
  • Malpractice claims from the COVID-19 pandemic: more questions than answers

    Robert E. White, Jr.
  • Why Department of Homeland Security leadership is vital for battling the COVID-19 pandemic

    Teshamae Monteith, MD
  • Medical education in the COVID-19 pandemic can’t be ignored

    Casey Hribar and Carolyn S. Quinsey, MD
  • The COVID-19 pandemic is a catalyst for reimagining future health care delivery

    Imelda Dacones, MD

More in Conditions

  • Overcoming Parkinson’s: a journey of laughter and resilience

    Cynthia Poire Mathews, FNP
  • The untold struggles patients face with resident doctors

    Denise Reich
  • Maximize sleep efficiency with stimulus control

    Pedram Navab, DO
  • The endless waves of chronic illness

    Michele Luckenbaugh
  • Surviving and thriving after life’s most difficult moments

    Rebecca Fogg, MBA
  • The surprising power of Play-Doh in pediatric care: How it’s bringing families together

    Alexander Rakowsky, MD
  • Most Popular

  • Past Week

    • The real cause of America’s opioid crisis: Doctors are not to blame

      Richard A. Lawhern, PhD | Meds
    • It’s time for C-suite to contract directly with physicians for part-time work

      Aaron Morgenstein, MD & Corinne Sundar Rao, MD | Physician
    • What is driving physicians to the edge of despair?

      Edward T. Creagan, MD | Physician
    • The untold struggles patients face with resident doctors

      Denise Reich | Conditions
    • The psychoanalytic hammer: lessons in listening and patient-centered care

      Greg Smith, MD | Conditions
    • Safe sex for seniors: Dispelling myths and embracing safe practices [PODCAST]

      The Podcast by KevinMD | Podcast
  • Past 6 Months

    • The real cause of America’s opioid crisis: Doctors are not to blame

      Richard A. Lawhern, PhD | Meds
    • Nobody wants this job. Should physicians stick around?

      Katie Klingberg, MD | Physician
    • The vital importance of climate change education in medical schools

      Helen Kim, MD | Policy
    • The fight for reproductive health: Why medication abortion matters

      Catherine Hennessey, MD | Physician
    • Resetting the doctor-patient relationship: Navigating the challenges of modern primary care

      Jeffrey H. Millstein, MD | Physician
    • It’s time for C-suite to contract directly with physicians for part-time work

      Aaron Morgenstein, MD & Corinne Sundar Rao, MD | Physician
  • Recent Posts

    • Safe sex for seniors: Dispelling myths and embracing safe practices [PODCAST]

      The Podcast by KevinMD | Podcast
    • Overcoming Parkinson’s: a journey of laughter and resilience

      Cynthia Poire Mathews, FNP | Conditions
    • The untold struggles patients face with resident doctors

      Denise Reich | Conditions
    • Maximize sleep efficiency with stimulus control

      Pedram Navab, DO | Conditions
    • The Iranian diaspora’s fight for liberty: Overcoming challenges in the largest women’s rights movement of our century

      Montreh Tavakkoli, MD | Physician
    • Surviving clinical rounds: tips and tales from a pediatric hematologist-oncologist [PODCAST]

      The Podcast by KevinMD | Podcast

Subscribe to KevinMD and never miss a story!

Get free updates delivered free to your inbox.


Find jobs at
Careers by KevinMD.com

Search thousands of physician, PA, NP, and CRNA jobs now.

Learn more

Leave a Comment

Founded in 2004 by Kevin Pho, MD, KevinMD.com is the web’s leading platform where physicians, advanced practitioners, nurses, medical students, and patients share their insight and tell their stories.

Social

  • Like on Facebook
  • Follow on Twitter
  • Connect on Linkedin
  • Subscribe on Youtube
  • Instagram

CME Spotlights

From MedPage Today

Latest News

  • How This Doctor Found Purpose After a Devastating Injury
  • House Lawmakers Squabble Over HHS Budget
  • Infant Formula Crisis Exposed FDA and Industry Failings, Lawmakers Say
  • Building Vaccine Trust Among the General Public
  • Is It Business as Usual for the Drug Industry?

Meeting Coverage

  • Phase III Trials 'Hit a Home Run' in Advanced Endometrial Cancer
  • Cannabis Use Common in Post-Surgery Patients on Opioid Tapering
  • Less Abuse With Extended-Release Oxycodone, Poison Center Data Suggest
  • Novel Strategies Show Winning Potential in Ovarian Cancer
  • Children Do Well With Fewer Opiates After Surgery
  • Most Popular

  • Past Week

    • The real cause of America’s opioid crisis: Doctors are not to blame

      Richard A. Lawhern, PhD | Meds
    • It’s time for C-suite to contract directly with physicians for part-time work

      Aaron Morgenstein, MD & Corinne Sundar Rao, MD | Physician
    • What is driving physicians to the edge of despair?

      Edward T. Creagan, MD | Physician
    • The untold struggles patients face with resident doctors

      Denise Reich | Conditions
    • The psychoanalytic hammer: lessons in listening and patient-centered care

      Greg Smith, MD | Conditions
    • Safe sex for seniors: Dispelling myths and embracing safe practices [PODCAST]

      The Podcast by KevinMD | Podcast
  • Past 6 Months

    • The real cause of America’s opioid crisis: Doctors are not to blame

      Richard A. Lawhern, PhD | Meds
    • Nobody wants this job. Should physicians stick around?

      Katie Klingberg, MD | Physician
    • The vital importance of climate change education in medical schools

      Helen Kim, MD | Policy
    • The fight for reproductive health: Why medication abortion matters

      Catherine Hennessey, MD | Physician
    • Resetting the doctor-patient relationship: Navigating the challenges of modern primary care

      Jeffrey H. Millstein, MD | Physician
    • It’s time for C-suite to contract directly with physicians for part-time work

      Aaron Morgenstein, MD & Corinne Sundar Rao, MD | Physician
  • Recent Posts

    • Safe sex for seniors: Dispelling myths and embracing safe practices [PODCAST]

      The Podcast by KevinMD | Podcast
    • Overcoming Parkinson’s: a journey of laughter and resilience

      Cynthia Poire Mathews, FNP | Conditions
    • The untold struggles patients face with resident doctors

      Denise Reich | Conditions
    • Maximize sleep efficiency with stimulus control

      Pedram Navab, DO | Conditions
    • The Iranian diaspora’s fight for liberty: Overcoming challenges in the largest women’s rights movement of our century

      Montreh Tavakkoli, MD | Physician
    • Surviving clinical rounds: tips and tales from a pediatric hematologist-oncologist [PODCAST]

      The Podcast by KevinMD | Podcast

MedPage Today Professional

An Everyday Health Property Medpage Today iMedicalApps
  • Terms of Use | Disclaimer
  • Privacy Policy
  • DMCA Policy
All Content © KevinMD, LLC
Site by Outthink Group

Leave a Comment

Comments are moderated before they are published. Please read the comment policy.

Loading Comments...