Post Author: Marc Arginteanu, MD

Marc Arginteanu is a neurosurgeon and author of Azazel’s Public House.

Marc Arginteanu is a neurosurgeon and author of Azazel's Public House.

How gut bacteria shape your mental health and mood

Conditions
August 8, 2025

The gut-brain axis is a key player in mental illnesses such as schizophrenia, bipolar disorder, depression, and anxiety.

The intestinal microbiome (the foundation of the gut-brain axis) influences brain function through bidirectional communication via neural (vagus nerve), immune (cytokines), and metabolic pathways. Microbiota alterations may also impair hypothalamic-pituitary-adrenal axis regulation, which, in turn, affects both psychological stress level (cortisol) and whole-body hormonal balance. What’s more, microbial metabolites (such as short-chain fatty …

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How the shingles vaccine could help prevent dementia

Conditions
June 18, 2025

Did you have chickenpox as a kid?

If the answer is yes (which it is for most of us), you’re at risk of getting shingles. Shingles is caused by the varicella-zoster virus, the same virus that causes chickenpox. After one recovers from chickenpox, the virus remains dormant in one’s nerve cells. Later in life, if the virus reactivates (which depends on factors like age, stress, or a weakened immune system), it …

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Diabetes and Alzheimer’s: What your blood sugar might be doing to your brain

Conditions
May 20, 2025

There’s an ever-growing body of evidence to suggest that diabetes contributes to the development of Alzheimer’s disease. Some even go so far as to dub Alzheimer’s disease “diabetes type III.”

How might diabetes cause Alzheimer’s disease?

It’s the sugar: Chronic high blood sugar (hyperglycemia) can damage blood vessels, including those in the brain. This vascular damage reduces oxygen and nutrient delivery to brain cells, increasing …

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Do microplastics cause dementia?

Conditions
March 5, 2025

Let’s begin by understanding the scope of the dementia problem: According to data from Alzheimer’s Disease International, before you finish reading this sentence, someone, somewhere in the world will have developed dementia. Here comes another sentence, and there goes another new case of dementia. There goes another. And so on.

In 2020, the organization estimated that more than fifty-five million people across the globe were suffering from dementia. What’s more, this …

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A neurosurgeon’s 23 simple things you can do (in five minutes or less) to improve your brain health

Conditions
December 5, 2024

Here are 23 simple things you can do (in five minutes or less) to improve your brain health. Do one of them each day. Keep it up for a few short weeks and your brain will sing your praises.

Attitude of gratitude

The act of being grateful improves mental health in a number of ways, such as making the grateful person less prone to depression and fostering stronger relationships. Becoming more grateful …

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A hike filled with color is mind magic

Physician
November 10, 2024

Sure, going on a hike is great exercise. Every step brings you closer to your healthiest body. But did you know, hiking confers brain benefits? What’s more, if you do it right, hiking is magic for your mind. If you’re feeling scattered and your mind is drifting without direction, a properly curated hike can lead you to the right mental path. The color of your hike (green, blue, or red) …

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When technology merges with humanity

Conditions
September 10, 2024

An excerpt from Nephilim.

“Those eggs really hit the spot, right?”

“I’d love some more,” he answered.

“Sure,” Zdenek responded. “One or two?”

“How many do we have?”

Before long, James had wolfed down nine eggs.

“I wonder if it’s the choline,” Zdenek mused as James shoveled. “Eggs have a boatload of choline. Maybe she’s craving it. Orange that is.” James hadn’t touched his toast. “Choline, you know? It might help my baby merge with …

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Mediterranean diet boosts teen academic success

Conditions
August 14, 2024

In 2024, Chilean scientists reported their findings on interesting research. They investigated the correlation between adolescent academic achievement and eating style. The researchers studied over a thousand kids between the ages of ten and fourteen.

A portion of the kids enjoyed a balanced and healthy Mediterranean diet. When they used oil, it was most likely extra-virgin olive oil. They packed their plates with boatloads of vegetables, fruits, cereals, nuts, and …

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Cinnamon versus brain cancer, Alzheimer’s disease, and insomnia

Conditions
July 13, 2024

I’ve always adored cinnamon. Its aroma warms the cockles of my heart, and its flavor makes me feel as if I’m wrapped up in an old fairy tale. However, I was floored when I reviewed some of the latest research regarding the effects of cinnamon on brain health.

Cinnamon is a type of laurel plant (believe it or not, there are almost three thousand members of the Lauraceae family). Cinnamon happens …

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Long COVID and your brain: the effect of virus and vaccines

Conditions
May 12, 2024

A bunch of symptoms, which may persist many months or even years after an acute COVID infection has cleared, have been described in the medical literature with increasing frequency since the onset of the pandemic. This constellation of findings has been dubbed “long COVID.” Long COVID’s effects on the brain, in particular, have certainly been in the news, and it’s also been popping up in the medical literature. So, what’s …

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Can you predict Alzheimer’s? New research on early detection.

Conditions
March 27, 2024

You can’t treat something until you know it’s there. Currently, there’s no cure for Alzheimer’s disease (AD) but earlier diagnosis may lead to better understanding of how the disease inexorably progresses, which in turn may lead to prevention of AD and ultimately eradication of this horrific scourge. The latest breakthroughs in earlier diagnosis and even perhaps pre-diagnosis have involved lumbar punctures, brain MRIs, eye exams, and blood tests.

A 2024 study, …

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Heart-stopping brain surgery: a surgeon’s harrowing dilemma

Conditions
February 29, 2024

An excerpt from of Paint and Pancakes.

The epicenter of Jane’s cancer occupied some very expensive real estate between Broca’s area and the motor strip. Her ability to speak and form coherent words resided in Broca’s. A little further back was the Motor Strip, which controlled the movement of the right side of her body.

It all looks the same … so damned normal. Mike cleared his throat. High-price …

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Ketones may be the key to unlocking a healthier brain

Conditions
January 29, 2024

You’ve undoubtedly heard the buzzwords: ketogenic diet, intermittent fasting. I don’t have much of an opinion about what that all does for your waistline, but I venture to say that ketones may benefit your brain.

Some doctors have recommended, with rock-solid evidence, diets that increase brain ketone levels as part of the regimen to treat drug-resistant epilepsy in children. Others claim that high ketone levels are like a magic bullet and …

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Protect your brain with a good night’s sleep

Conditions
December 15, 2023

No one knows exactly why we need to sleep, but we certainly do. Although the brain can’t thrive on sleep alone, good sleep is an essential ingredient necessary to keep your brain functioning at its best. New research is shedding light on how a good night’s sleep may protect your brain from neurodegenerative diseases.

In 2022, Canadian scientists evaluated the medical literature regarding sleep apnea and its link to the risk …

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The brain science behind acupuncture

Conditions
November 22, 2023

There are those who believe acupuncture to be a bunch of mumbo jumbo. I’m convinced it works, though. Acupuncture was first performed thousands of years ago, and it’s still being done today. That alone should tell you there’s something to it. Early practitioners believed they were balancing life force and rhythm. Modern science has proven that acupuncture may alter brain circuitry, change brain cell anatomy, and improve brain blood flow.

Way …

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I’m a neurosurgeon. Social media may change your kid’s brain.

Conditions
October 11, 2023

A 2023 study of middle school-aged children laid out some alarming findings. Scientists recruited more than one hundred and fifty children, all aged twelve, from rural North Carolina public schools. The children were surveyed regarding their social media usage, including Facebook, Instagram, and Snapchat. Some of the kids rarely checked social media (one time or less per day), while others were glued to their screens, checking social media more than …

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Why do smart doctors sink money into silly investments?

Finance
October 13, 2022

People who’ve done what it takes to earn a medical degree are typically pretty special. Most doctors spend reasonably, invest wisely and incubate a healthy nest egg: a recipe for a comfortable retirement. But some doctors are profligate and foolishly fall prey to hare-brained financial schemes. On the outside, they seem just like their financially savvy brethren.

But, neuroscientifically speaking, something is lurking under the surface of the silly-money cohort. Let’s …

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2 questions you should ask when choosing a surgeon

Physician
July 8, 2022

If you or a loved one needs surgery, you’re very likely terrified. You also may be shopping around to find a surgeon. Of course, you’ll want the best. (I’ve never heard someone say, “I’d like the most average surgeon I can find.”) There are lots of factors to take into account. But here are two questions you might not otherwise have thought to ask:

1. When you sit in the surgeon’s …

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The baby formula shortage puts your baby’s brain at risk

Conditions
May 23, 2022

The baby formula shortage has morphed into a full-blown ongoing crisis. Many stores report that more than half of baby formula products are out of stock. Babies who are six months old or younger should only be fed breast milk or formula. Any substitute may be nutritionally incomplete and may cause babies to have permanent problems in brain development.

What are the essential brain ingredients in the leading baby formulas?

Docosahexaenoic acid …

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