The ibuprofen COVID-19 paradox

With the surge of information surrounding COVID-19 released in the news this year, an interesting concern arose regarding ibuprofen’s use in patients with COVID-19. In March of 2020, French authorities were the first to investigate anecdotal reports of severe COVID-19 infection in patients who had taken ibuprofen.

The initial concern involved the ACE-2 receptor. The theoretical concern was that NSAIDs (nonsteroidal anti-inflammatory drugs) such as ibuprofen might …

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