The National Institute of Aging (NIA) just announced $73 million over five years to fund two new research centers. "The Alzheimer Centers for the Discovery of New Medicines are designed to diversify and reinvigorate the Alzheimer's disease drug development pipeline," says the NIA online. The AlzForum.org has more details, quoting researchers saying they will change the direction away from amyloid-beta and tau (the presumed ...

Read more...

The way I learned the Golden Rule was: "Do unto others as you would have them do unto you." Basically, it's from the New Testament, but the concept goes way back to pre-Christian ancient civilizations in Babylonia, Egypt, India, and China. So here I am, just trying to do my best as a spousal caregiver, and I started to realize that if I were to take the Golden Rule literally — ...

Read more...

Two prestigious medical journals published studies involving Alzheimer disease (AD) and amyloid beta in successive weeks; both were paired with guest expert commentaries (editorials).  One editorial, about a drug study, also reviewed several other failures in anti-amyloid therapy and stated: “To be blunt, A-beta [amyloid] lowering seems like an ineffective approach….” The other editorial had an encouraging attitude toward amyloid PET imaging as part of the diagnostic ...

Read more...

Dementia patients want effective drugs. Five years ago, the Food and Drug Administration (FDA) proposed changes to speed drug approvals for Alzheimer’s disease (AD). No new drugs have been approved. This year, a new FDA draft guidance discusses considering biomarker data and changing cognitive evaluations for accelerated approvals. Would that help make effective drugs available, or are we lowering our expectations? Numerous dementia agents have failed current ...

Read more...

A baby acutely ill with leukemia seems like the polar opposite of a woman with Alzheimer’s disease (AD), with her slow, insidious deterioration. Yet each disease can be progressive and fatal. I’ve cared for both, in different ways.  Can a childhood cancer doctor like me have insights about that other end of medicine, older adults with dementia? As a husband and caregiver, confronting my wife’s Alzheimer’s disease, I am appalled by the ...

Read more...

1 Pages

Most Popular

Join 150,000+ subscribers

Get the best of KevinMD in your inbox

Sign me up! It's free. 
close-link
✓ Join 150,000+ subscribers 
✓ Get KevinMD's 5 most popular stories
Subscribe. It's free.