Meds

Can morphine help prevent post-traumatic stress disorder (PTSD)?

Originally posted in MedPage Today

by Todd Neale, MedPage Today Staff Writer

The use of morphine may prevent the development of post-traumatic stress disorder (PTSD) in military personnel injured in combat, an observational study showed.

Those who received the drug during resuscitation or trauma care were about half as likely to later develop PTSD (OR 0.47, P<0.001), according to Troy Lisa Holbrook, PhD, …

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When are stroke patients more likely to receive clot busting drugs?

Originally published in MedPage Today

by Todd Neale, MedPage Today Staff Writer

Patients suffering an acute ischemic stroke are about 20% more likely to receive clot-busting therapy with tissue plasminogen activator (tPA) if they arrive at the hospital on the weekend, a retrospective study showed.

However, there was no difference in rates of inhospital mortality based on the time of admission, Abby …

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How psychiatrists may be giving their patients too many drugs

Originally published in MedPage Today

by John Gever, MedPage Today Senior Editor

Psychiatrists who prescribe drugs for their patients today usually give more than one at a time, often with little scientific basis, researchers said.

About 60% of patients with psychiatrist office visits leading to a drug prescription received at least two medications in 2005-2006, according to government survey data analyzed by Ramin …

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Do neuroenhancement pills really improve attention, memory, or cognition?

Originally published in HCPLive.com

by Victor G. Dostrow, MD

The Internet is filled with reports of remarkable cognitive enhancement with various nostrums.

Many are not regulated, and the pages are typically associated with glowing testimonials and a link to sign up for uninterrupted (and uninterruptible) delivery of the miracle substance. More to the point of this post, other blogs, reports, and forum comments opine as to notable benefits of taking prescription medications marketed …

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Don’t use kitchen spoons to measure drug dosages

Originally published in MedPage Today

by Todd Neale, MedPage Today Staff Writer

Individuals using standard spoons from their home kitchen to dispense liquid medications may be pouring too little or too much of the drugs, researchers found.

Among volunteers trying to pour a teaspoonful of cold and cough medicine, using a slightly larger spoon resulted in underdosing and using a much larger …

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Depression severity predicts how well antidepressant drugs will work

Originally published in Insidermedicine

The benefits of antidepressant therapy increase with the severity of underlying depression, according to a meta-analysis published in the Journal of the American Medical Association.

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What will the next big medical advance be?

Originally published in MedPage Today

by Michael Smith, MedPage Today North American Correspondent

It’s tough to make predictions, especially about the future.

That famous observation from baseball great Yogi Berra applies in spades to medicine.

What technological advance or new insight will shape the next few years? As Yogi noted, it’s tough to predict:

It could be — as Leif Ellisen, MD, PhD, thinks — tumor genotyping.

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How osteopenia became a disease and made Fosamax popular

How did osteopenia, the precursor to osteoprosis, come about?

Fascinating story from NPR, detailing how a drug company popularized the condition in order to expand the market for their drug, Fosamax.

Osteopenia is diagnosed via a bone density study showing a “T-score” between -1.0 and -2.5. But how that definition came about was quite arbitrary.

In 1994, a group of researchers from the World Health Organization poured over data, and eventually, …

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Cardiologists discuss how far myocardial infarction management has come

Originally published in MedPage Today

by Peggy Peck, MedPage Today Executive Editor

“What we did for patients with acute MI was place them in a cool, dark place. Give them morphine for pain and lidocaine to prevent arrhythmias and hope for the best.”

The speaker is Steven Nissen, MD, director of Cardiovascular Medicine at the Cleveland Clinic. He is describing standard care 25 …

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How effective is a single dose of H1N1 vaccine for adults?

Originally published in Insidermedicine

Healthy adults require only a single dose of H1N1 vaccine in order to be optimally protected, according to research published in the New England Journal of Medicine.

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How women can benefit from oral contraceptive pills

Originally posted in MedPage Today

by Nancy Walsh, MedPage Today Contributing Writer

Hormonal contraceptives have a variety of noncontraceptive uses, ranging from common problems such as dysmenorrhea to severe conditions such as premenstrual dysphoric disorder, according to a new practice bulletin from the American College of Obstetricians and Gynecologists (ACOG).

“Combined hormonal contraceptives can correct menstrual irregularities resulting from oligo-ovulation or anovulation and …

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How medication mistakes happen in the hospital

Originally published in MedPage Today

by Katrina Woznicki, MedPage Today Contributing Writer

Hospitalized patients were often clueless when asked about their medications, with almost all of them unable to name all their medications and many leaving out as many as a half-dozen drugs they have been prescribed, according to a small survey of patients in a Colorado hospital.

Ninety-six percent of the …

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Rich countries are selfish when it comes to vaccine safety

A recent article from Newsweek discusses some of the long-term benefits of vaccines.

But it’s a section on the rich nation-poor nation dichotomy towards vaccine safety that’s most fascinating. The authors observe that better educated nations are those with the most vigorous opposition to vaccines. The United States, for instance, has many who simply refuse to be given the H1N1 vaccine – a benefit that’s not available to many …

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What the H1N1 vaccine recall means for kids

Originally posted in MedPage Today

by Todd Neale, MedPage Today Staff Writer

Sanofi Pasteur has recalled about 800,000 pediatric doses of its vaccine against pandemic H1N1 influenza because of low potency, the CDC announced, but the agency is not calling for revaccinations.

The recalled doses come from four lots of 0.25-mL prefilled syringes for pediatric use in both 10-packs (lot numbers UT023DA, …

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The risk of death from OxyContin and other narcotic drugs

Originally published in Insidermedicine

The alarming risk of death associated with the use of prescribed narcotic drugs, particularly OxyContin, is highlighted in a study published in the latest issue of the Canadian Medical Association Journal.

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Ecstasy increases sleep apnea risk

Originally published in Insidermedicine

Repeated use of the club drug MDMA, which is known on the street as “ecstasy” increases the risk of the breathing disorder known as sleep apnea, according to research published in journal Neurology.

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Tamiflu kills babies, and other H1N1 flu pandemic misconceptions

Originally published in MedPage Today

by Todd Neale, MedPage Today Staff Writer

As one of the two MedPage Today writers on full-time H1N1 duty since the beginning of the outbreak in April, I feel like I know the issues well enough to help clear up misconceptions when they come up in conversation.

medpage-today1The other day, just such a situation presented itself. An …

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Pharma, evidence, and trust

by David Rind, MD

A number of the other blogs that have noted the existence of this blog seem to have “Pharma” in their titles in one way or another, and the implication is not that the blogger likes much about Big Pharma.

In the late 1990s, when I was spending much of my clinical time providing HIV care, I was a defender of Pharma on Usenet, at least as it related …

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Which drugs increase the risk of falling in the elderly?

Originally published in Insidermedicine

Three distinct types of drugs that affect mental processes can increase the risk of falling when taken by adults over 60, according to research published in the latest edition of the Archives of Internal Medicine.

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