The day I first watched ketamine lift a human being out of despair, I was standing in a quiet room at the National Institute of Mental Health. The fluorescent lights hummed, the monitor ticked, and a young adult who had been drowning for months came up for air. Hours, not weeks. That speed rewired me as much as it rewired their brain. In the early 2000s, most of us were …
A psychiatrist’s 20-year journey with ketamine
Funding from direct-to-consumer (DTC) “ask your doctor” drug ads has captured news media outlets and all but blocked important health stories like these. Read on.
1. “Hormone replacement therapy” (HRT) is back.
It is said that those who forget the past are doomed to repeat it, and nowhere is this more evident than the re-marketing of HRT to menopausal women who do not remember the first debacle (which increased the risk …
How drug companies profit by inventing diseases
Every 24 hours, at least one person dies from a preventable medication error. Every hour, countless others suffer complications that could have been avoided with better systems. Yet despite billions invested in health care technology and training, these numbers are not improving.
Here’s the uncomfortable truth: We have been solving the wrong problem.
For decades, health care has treated medication errors like individual failures — a tired nurse, a distracted doctor, a …
Every medication error is a system failure, not a personal flaw
In recent years, kratom, a botanical herb indigenous to Southeast Asia, has surged in popularity across the United States.
Marketed aggressively online and sold openly in vape shops, convenience stores, and specialty herbal outlets, kratom is often portrayed as a natural remedy, an herbal escape from chronic pain, anxiety, and opioid withdrawal. But beneath the alluring veneer of wellness and relief lies a dangerous, largely unregulated substance capable of causing severe …
Why kratom addiction is the next public health crisis
The FDA is failing rare disease patients. I’m one of them.
I’ve been on elamipretide for three years now. It is the only treatment that has made a meaningful difference in my life with primary mitochondrial myopathy—a degenerative genetic condition that impairs how my cells convert food and oxygen into energy. Mitochondria provide over 90 percent of the energy our bodies need; when they fail, the highest-demand tissues—like muscle, brain, and …
FDA delays could end vital treatment for rare disease patients
More than 78 million Americans rely on Medicaid or CHIP for their health care. Yet many still cannot access FDA-approved digital therapeutics because their state does not include them in covered benefits.
Prescription digital therapeutics (PDTs) are software-based treatments authorized by the FDA. They are delivered through smartphones or tablets and are used to manage conditions such as substance use disorder, ADHD, diabetes, and chronic insomnia. For people who face long …
Pharmacists are key to expanding Medicaid access to digital therapeutics
In today’s evolving health care environment, value-based care is reshaping the future of medicine. The push toward value-based care demands innovative, cost-effective, and patient-centered solutions. A promising yet underutilized strategy is medicine repurposing, the practice of using existing medicines for new therapeutic purposes. Drug repurposing provides a strategic pathway to improving health outcomes while minimizing costs. A compelling example of this approach is the use of clonidine, a long-established cardiovascular …
How medicine repurposing enables value-based pain management and insomnia therapy
I won’t be using CVS pharmacies anymore. Sure, I may still need to send prescriptions their way as a physician—but as a consumer, I’m done.
Why?
CVS has recently implemented a new phone system that forces callers to leave a voicemail instead of waiting on hold. The idea is to streamline operations, letting pharmacy staff return calls when they have time. It’s supposed to manage call volume, reduce wait times, and shield …
Forced voicemail and diagnosis codes are endangering patient access to medications
In 1971, President Nixon initiated a battle that would reshape the United States: The War on Drugs. As a key part of that campaign, he enacted the Controlled Substances Act (CSA), which authorized the Drug Enforcement Administration (DEA) to categorize modern-day controlled substances into 5 “schedules” based on their “medical use, potential for abuse, and safety or dependence liability.” They range from Schedule I, which are substances with no …
From stigma to science: Rethinking the U.S. drug scheduling system
It is said that 57 percent of U.S. doctors receive drugmaker/industry funding and 66 percent of U.S. adults are now on prescription drugs. Any correlation?
Drug ads now cast such a wide “symptom net,” comedian Chris Rock said he expected to hear, “Do you fall asleep at night and wake up in the morning? You might be suffering from ….”
Here are six ways drugmakers hijack U.S. medicine
Diagnosing. Once upon a time …
How drugmakers manipulate your health from diagnosis to prescription
As a health care professional, I’ve often observed how one critical aspect of medication safety and efficacy gets overlooked: food-drug interactions.
Every day, we prescribe and dispense powerful medications — but what patients eat alongside those medications can completely alter their effects.
This isn’t just a pharmacy concern. It’s a multidisciplinary issue that deserves greater attention from physicians, pharmacists, and patient educators.
The physician’s role: Asking the right questions
We often do a solid …
The food-drug interaction risks your doctor may be missing
The importance of diversity in clinical trials is well-documented, yet unfortunately the lack of diversity still occurs at an alarming rate. As a result, we continue to have less effective treatments, poorer health outcomes, one-size-fits-all medicine that falls short of many patients, and many more negative impacts on health care.
The reason for lack of diversity in clinical trials is similarly known, with language barriers, limited access to health care facilities …
Why retail pharmacies are the future of diverse clinical trials
Rifaximin, a minimally absorbed antibiotic, has become a cornerstone therapy for several gastrointestinal disorders, including irritable bowel syndrome with diarrhea (IBS-D) and hepatic encephalopathy. Despite its established use, access to rifaximin varies significantly across global markets, with cost barriers posing challenges in some regions. In contrast, in many Asian countries, the same medication is available at a fraction of the price, raising important questions about pharmaceutical pricing practices and access …
Why does rifaximin cost 95 percent more in the U.S. than in Asia?
Imagine waking up one morning to a bold headline screaming: “New Global Law: All Antidepressants Abolished!” Just like that, no more Prozac, no more Zoloft—no more of those little pills that have helped millions keep their balance while navigating life’s emotional tightrope. Pharmacy shelves are wiped clean overnight, and suddenly, one of the pillars of modern mental health care is gone.
Before you clutch your chest and start breathing into a …
A world without antidepressants: What could possibly go wrong?
For years, weight loss has been sold as a simple math problem: eat less, move more, and the pounds will melt away. But if that were true, we wouldn’t have an obesity epidemic affecting over 40 percent of adults in the U.S.
Now, a new class of medications—GLP-1 receptor agonists like semaglutide (Ozempic, Wegovy) and tirzepatide (Mounjaro, Zepbound)—are changing the game. People who have struggled with their weight for …
The truth about GLP-1 medications for weight loss: What every patient should know
As a health care writer and data analyst, I hear frequently from patients who are being denied safe and effective pain care due to unscientific bias on the part of U.S. health care agencies—and sometimes on the part of otherwise once-reputable medical journals. These are among millions of U.S. citizens who are now being deserted by the medical profession.
Thousands, overcome by their pain and depression, have already …
The hidden bias in how we treat chronic pain
“Once it’s in your body, there’s no taking it back.”
That’s what the infusion nurse told a friend of mine after administering the injection.
She had just started a biologic medication for an autoimmune condition. Immediately, her body reacted: nausea, then hives, then a terrifying tightening of her throat. She rushed back to the clinic. The IV steroids and Benadryl may have stopped the immediate effects, …
“Will I be asleep or awake during my procedure?” This is the first question many patients ask before oral surgery. It reveals a common misconception: That anesthesia works like a light switch.
It doesn’t.
Anesthesia exists on a spectrum with multiple options that can be tailored to your specific needs, procedure type, and anxiety level.
Beyond all-or-nothing
As an oral …
The anesthesia spectrum: Guiding patients through comfort options in oral surgery
Functional precision oncology is taking precision medicine to the next level. It is changing the way we fight cancer by testing a patient’s live tumor outside the body to determine the treatments most likely to work. This approach promises to double cancer response rates, improve survival, and reduce costs. It’s personal, data-driven, and long overdue, yet most cancer centers still don’t offer it.
Even many doctors are unaware that the standard …
Functional precision oncology: a game changer in cancer therapy
I absolutely hate prescribing medication to children.
I am quite worried when someone asks for my opinion on a sick child. I have some experience treating children during my internship and residency, yet I am pretty uncomfortable.
However, living in a lower middle-income country, where the average man already lives a difficult life due to high health care costs and limited income, health expenditure significantly impacts monthly finances. That is why people …
Why prescribing medicine to kids scares even experienced doctors
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