Test your medicine knowledge with the MKSAP challenge, in partnership with the American College of Physicians. A 64-year-old man is evaluated for a 2-year history of knee osteoarthritis. He has bilateral knee pain that worsens with walking. He has tried topical therapies, physical therapy, and acetaminophen, none of which has provided relief. The patient also has peripheral vascular disease, hyperlipidemia, and hypertension. Medications are hydrochlorothiazide, pravastatin, and a ...

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Top stories in health and medicine, July 3, 2014From MedPage Today:

  1. Proposal To Add 'Copper' Plans to Marketplace Raises Concerns. If you offer it, will they come? Insurers and some U.S. senators have proposed offering cheaper, skimpier "copper" plans on the health insurance marketplaces to encourage uninsured stragglers to buy.
  2. Childhood Malnutrition May Raise HTN Risk. Young adults who survived ...

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Top stories in health and medicine, June 23, 2014From MedPage Today:

  1. FDA: Testosterone Carries VTE Risk. Testosterone products can cause venous thromboembolism (VTE) even in patients without polycythemia, the FDA warned amidst ongoing cardiovascular risk assessment.
  2. Safety Foul-Up Exposes CDC Staff to Anthrax. A breakdown in safety procedures has exposed 84 CDC staffers in Atlanta to live anthrax.

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Top stories in health and medicine, June 16, 2014From MedPage Today:

  1. The Hobby Lobby Case: The Stakes for Birth Control. One of the most watched issues before the Supreme Court this term may turn on the question of religious freedom. But it will also likely determine how women will be able to access a key provision of the Affordable Care Act -- ...

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From MedPage Today:

  1. Primary Pain Points: 'Messing With the Computer'. "Messing with the computer takes the physician's head out of the exam," Jordan Grumet, MD, a primary care clinician in a small practice in Northbrook, Ill., told MedPage Today in response to the question "What frustrates you?"
  2. No Link Seen Between Vaccines and Lupus. Recent vaccination was not associated with an increased risk for the development ...

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Recently, an international research team led by Xavier Rodó published a fascinating study in PNAS suggesting that Kawasaki disease is caused by an agent transported by wind from farms in Northeast China.  This agent, possibly a fungal toxin, is responsible for triggering an exuberant immune response in children, causing the typical manifestation of the disease: fevers, rash, conjunctivitis, “strawberry tongue,” enlarged lymph nodes, and swelling of the extremities.  Untreated, Kawasaki disease can cause aneurysms of the coronary arteries, ...

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From MedPage Today:

  1. VA Top Doc Calls It Quits. Robert Petzel, the man in charge of healthcare for the Department of Veterans Affairs (VA), resigned Friday in the wake of a growing scandal over the care provided to veterans at various VA healthcare facilities.
  2. Steroid Use in RA More Common. More patients with rheumatoid arthritis today are initiating treatment with glucocorticoids (GCs) early in ...

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From MedPage Today:

  1. Possible Links Found Between Afib, Dementia. Heart rate and anticoagulation control may contribute to the relationship between atrial fibrillation and dementia.
  2. Excess Weight Weighs Heavily in Early RA Tx. Patients diagnosed with early rheumatoid arthritis who were overweight were less likely to achieve rapid disease control.
  3. FDA Slashes Starting Dose for Lunesta. Patients starting on the sleep drug eszopiclone ...

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It is noteworthy how certain vital and effective generic drugs for common diseases have become exorbitantly expensive. We are use to new pharmaceutical brands costing a small fortune. But generics, one of which goes back to use in Egyptian times? Really? Allopurinol and asthma inhalers that are cheap but effective medications have become unaffordable to those that need it the most: Simply stated, those that can't breathe and those that ...

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From MedPage Today:

  1. B-Cell Targeting Has Benefit in Severe Lupus. Although an inhibitor of B-cell activating factor failed to meet the primary endpoint in a phase II trial for lupus, beneficial effects were seen in patients with severe disease at baseline.
  2. Birth Weight, Breastfeeding Flag CVD Risk. Low birth weight (2.8 kg or smaller) and being breastfed for less than 3 months may increase ...

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