From MedPage Today:

  1. B-Cell Targeting Has Benefit in Severe Lupus. Although an inhibitor of B-cell activating factor failed to meet the primary endpoint in a phase II trial for lupus, beneficial effects were seen in patients with severe disease at baseline.
  2. Birth Weight, Breastfeeding Flag CVD Risk. Low birth weight (2.8 kg or smaller) and being breastfed for less than 3 months may increase ...

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From MedPage Today:

  1. Survey Favors Medicare Pay Data Release. Almost three of out five readers believe Medicare's release last week of data on what it paid individual doctors was a good idea.
  2. Risk Score Predicts Arthritis Progression. A risk score encompassing clinical characteristics, serologic findings, and imaging tests could be used to predict which antibody-positive patients are likely to go on to develop rheumatoid ...

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From MedPage Today:

  1. Two HCV Drugs Stronger Than One. A combination of the two newest drugs approved for hepatitis C virus (HCV) suggests that a strength of one overcomes a weakness of the other.
  2. % of Type 2 Diabetes Left Undiagnosed Declines. A lower percentage of type 2 diabetes cases is going undiagnosed than was the case in the past couple of decades.

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During our weekly physician conference,  I discussed a patient with a suspected autoinflammatory disease.  An elderly male, he had a history of recurrent fevers, hives, and elevated inflammatory markers, which had gone untreated for many years.  Eventually, he developed renal amyloidosis, and was finally referred to rheumatology clinic for further evaluation.  Although he had many of the classic signs and symptoms of an autoinflammatory disease, his physicians had not recognized ...

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From MedPage Today:

  1. 3 Key Strategies for ACO Success. More than 400 accountable care organizations (ACOs) exist across the country, and physician groups have overtaken hospitals as the largest backers of ACOs.
  2. Esophagitis May Come When Allergy Goes. After a child outgrows a food allergy, eosinophilic esophagitis (EoE) can emerge independently from the same trigger.
  3. Patch May Be Safer Peanut Allergy Therapy. ...

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From MedPage Today:

  1. A Targeted Treatment for Scleroderma? A monoclonal antibody that binds to the type 1 interferon-alpha receptor showed an acceptable safety profile in a phase I trial for systemic sclerosis, but efficacy was less clear.
  2. CMS: More 'Meaningful Use' Exemptions Coming. Some healthcare providers struggling to meet the second stage of the incentive program for electronic health records (EHRs) may receive a ...

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Test your medicine knowledge with the MKSAP challenge, in partnership with the American College of Physicians. A 32-year-old woman is evaluated following a diagnosis of chronic fatigue syndrome. She has a several-year history of chronic disabling fatigue, unrefreshing sleep, muscle and joint pain, and headache. A comprehensive evaluation has not identified any other medical condition, and a screen for depression is normal. Her only medications are multiple vitamins and ...

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From MedPage Today:

  1. Gout: Obesity's Stealth Disease. Once known as "the disease of kings," gout today clearly is a disease of commoners as well, and although it's on the rise.
  2. Can Statins Delay Death in Diastolic HF? Statins may have a role in reducing mortality in patients with heart failure and preserved ejection fraction (HFpEF).
  3. MS: Slow Progression With Vitamin D? Patients ...

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Many years ago, Alfred Korzybski wrote that "the map is not the territory." Gregory Bateson went on to argue that the map, which represents reality, is not the reality. This distinction has implications for the role of patient voice in health care planning and policy. Today, many organizations are making serious attempts to include the patient voice in policy and decision-making. Unfortunately, more than a few of them are ...

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From MedPage Today:

  1. Bystander CPR Better When More People Help. Cardiac arrest victims were more likely to receive good-quality bystander-initiated cardiopulmonary resuscitation (CPR) if multiple people assisted.
  2. New Guidelines Reflect Gout Evidence. A multinational group of experts has developed a set of 10 recommendations for the diagnosis and treatment of gout, derived from the "3e" initiative -- evidence, expertise, exchange -- and based on ...

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