The power of placebos has long been known. People who believe that they are taking an effective drug frequently feel better. In fact, prior to the discovery of penicillin, it is likely that the placebo effect accounted for much of the benefit of medical care. A study published in the journal Neurology makes an interesting connection between the magnitude of the placebo effect and the medication’s perceived price. The study enrolled 12 ...

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Test your medicine knowledge with the MKSAP challenge, in partnership with the American College of Physicians. A 58-year-old woman is seen for a follow-up evaluation of Parkinson disease, which she has had for 12 years. She was initially treated with ropinirole to which levodopa-carbidopa was added as the disease progressed. After 5 years of good control on medication, she began to experience involuntary generalized twisting and writhing movements ...

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medpagetodayFrom MedPage Today: Long-Term Danger for Kids' Tackle Football? Cognitive impairments in retired professional football players with behavioral or mental complaints were more pronounced in those who had played tackle football prior to age 12. Skipping Doses to Save $$$. Nearly 8% of adults in the U.S. did not take their medications ...

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medpagetodayFrom MedPage Today:

  1. Current Flu Vaccine Half as Effective as Previous Years. People receiving this year's seasonal influenza vaccine are 23% less likely to seek medical treatment for flu-type symptoms relative to unvaccinated individuals, according to an interim CDC estimate based on reports submitted so far for the current season.
  2. New Board ...

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medpagetodayFrom MedPage Today:

  1. Should FDA Change Metformin's Black Box Warning? Diabetes experts are building a case to lift restrictions on using metformin in patients with moderate chronic kidney disease.
  2. Tacrolimus for Induction in Lupus Nephritis? Tacrolimus was found to be noninferior to mycophenolate mofetil (Cellcept) for lupus nephritis induction therapy when given ...

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I once wrote about the communication difficulties caused by electronic medical records systems. The response on Twitter ranged from sentiments including everything from “right on, sister” to “greedy doctors are only complaining about EMRs because of their price tag.” The disconnect between policy wonk’s (and EMR vendor’s) belief in the transformative power of EMRs and exasperated clinician users of these products is jaw-dropping. Physicians are often labeled as ...

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Test your medicine knowledge with the MKSAP challenge, in partnership with the American College of Physicians. A 76-year-old woman is evaluated for a 1-day history of headache, left eye pain, nausea and vomiting, seeing halos around lights, and decreased visual acuity of the left eye. She has type 2 diabetes mellitus, hypertension, and atrial fibrillation. Medications are metformin, digoxin, metoprolol, hydrochlorothiazide, and warfarin. On physical examination, temperature is 36.8 ...

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medpagetodayFrom MedPage Today:

  1. Gene Test Has Promise for Nailing DCIS Recurrence Risk. A multigene panel predicted recurrence risk in ductal carcinoma in situ (DCIS), according to a population-based study.
  2. Docs, Guns, and Smokes. One day in clinic, 2 years ago, a patient handed Adam Goldstein, MD, MPH, a request for a concealed ...

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It started with a mild case of nausea and got progressively worse. I became dizzy and shaky, but tried to ignore it. There was work to be done that afternoon. We were moving boxes into storage at my in-laws’ house in Michigan, and I needed to be strong. I carried boxes on unsteady feet, catching myself before bumping into walls. By early evening my legs were wobbly, and I felt ...

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medpagetodayFrom MedPage Today:

  1. Renal Denervation: Not Dead Yet? A new analysis of the study that derailed the promise of catheter-based renal denervation may breathe new life into the procedure.
  2. 3 Ways to Select ICU Kids for Seizure Monitoring. Not all children with severe brain injuries need to be monitored for subclinical seizures, ...

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