Test your medicine knowledge with the MKSAP challenge, in partnership with the American College of Physicians. A 46-year-old woman is evaluated before undergoing a dental cleaning procedure involving deep scaling. She has a history of mitral valve prolapse without regurgitation and also had methicillin-resistant Staphylococcus aureus (MRSA) aortic valve endocarditis 10 years ago treated successfully with antibiotics. The patient notes an allergy to penicillin characterized by hypotension, hives, and ...

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medpagetodayFrom MedPage Today:

  1. FDA Advisory Committee Hesitates to Endorse Message of Safe Smokeless Tobacco. An FDA advisory panel were reluctant to recommend a gentler warning label for one brand of smokeless tobacco products at a committee hearing on Friday.
  2. The Skinny on Dementia and Being Skinny. Individuals with body mass index values ...

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medpagetodayFrom MedPage Today:

  1. Brain Cancer: Did '60 Minutes' Report Raise False Hope? A glioblastoma therapy touted in a "60 Minutes" report that aired Sunday evening, focusing on the use of the polio virus to treat glioblastoma, isn’t a particularly new idea and results are still unpublished -- but some oncologists are worried that patients ...

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If it weren’t for the coming together of people from all over the globe, the influenza pandemic of 1918, also known as the Spanish Flu, would not have had the devastating effect that it did. It is estimated that at one point this deadly strain infected one out of every five people on earth and ended up claiming the lives of approximately fifty million people (in comparison, nine million combatants ...

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Medicine is obsessed with numbers.  Or rather, journalists and medical administrators are.  Here are two related examples of how large a grain of salt one must put on numbers. Cardiac surgical procedures, like everything else in medicine, have quality indicators.  One of these is what we doctors call “30-day mortality.”  What this term means is that surgeons are evaluated in part on how many of the patients they operated on died ...

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medpagetodayFrom MedPage Today:

  1. OA Patients Don't Face Higher Heart Disease Risk. Neither radiographic nor clinical osteoarthritis (OA) was related to a greater risk for cardiovascular disease (CVD) in older patients.
  2. Senators to Providers, Industry: Lobby Harder on End-of-Life Care. A strong coalition is needed to transform care for the dying, said U.S. ...

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Many readers know that I favor empiric antibiotic treatment for adolescent/young adult pharyngitis when the clinical signs and symptoms strongly suggest a bacterial infection. I favor narrow target antibiotics and only in the patients with Centor scores of 3 or 4 (and perhaps some 2s when the patient looks very ill). This would exclude over 50 percent of patients from antibiotics. Most organisms already have developed resistance to penicillin, amoxicillin, and ...

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medpagetodayFrom MedPage Today:

  1. Opioid Abuse Drops, Then Levels Off. Making an abuse-deterrent formulation of OxyContin (oxycodone ) diminished abuse in the short term, but the reductions eventually hit a plateau.
  2. After Ebola, Measles Death Toll Could Be High. The death toll from post-Ebola measles outbreaks in three West African countries could rival ...

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medpagetodayFrom MedPage Today:

  1. MedPage Today at 10: Where We Have Been. Sometimes things go so right, that you get nervous. Really nervous. That's pretty much what happened when MedPage Today launched 10 years ago.
  2. Sepsis Readmissions May Be Correctable. It might be possible to prevent many of the hospital readmissions that occur ...

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It’s 2015, and we’re talking about measles. Not Enterovirus. Not Ebola. Not RSV. Not influenza. Instead, we’re talking about a historical virus that was declared eradicated from the United States in 2000. Most pediatricians who began practicing within the last 15 years have never even seen the disease. Measles starts as a high fever followed by a cough, runny nose (coryza), red and watery eyes (conjunctivitis), and tiny white spots inside the mouth ...

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