The tenets engendered by cancer have been slowly elucidated throughout the years. The hallmarks of cancer have been well documented by Douglas Hanahan and Robert Weinberg in Hallmarks of Cancer: The Next Generation. Some of these features are well known and are inclusive of sustained proliferative signaling, evading growth suppressions, and others clearly outlined in their review. These cellular processes have been discovered by basic science researchers and subsequently, modern ...

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asco-logoI recently attended the David Stroud Adolescent and Young Adult [AYA] Symposium at Keck Medicine of University of Southern California. It was a very interesting symposium with experts in adolescent and young adult cancer presenting on many different topics important for this population. There was also a panel of young adult cancer survivors, and this, for me, was a definite ...

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Test your medicine knowledge with the MKSAP challenge, in partnership with the American College of Physicians. A 54-year-old woman is evaluated for shortness of breath of 3 months' duration and a 4.5-kg (10-lb) weight loss over the preceding 2 months. She has a 35-pack-year smoking history. On physical examination, temperature is 36.9 °C (98.4 °F), blood pressure is 145/82 mm Hg, and pulse rate is 108/min. Oxygen saturation is ...

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medpagetodayFrom MedPage Today:

  1. Health IT: 'We Were Bound To Be Disappointed'. Robert Wachter, MD, works an hour north of Silicon Valley. Being surrounded by an "incredibly dynamic, vibrant IT ecosystem" contributed to a sense of disconnect for the associate chairman of medicine at the University of California San Francisco.
  2. Americans Miss WHO ...

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shutterstock_180321404 I have always been one of Angelina Jolie’s biggest fans.  The Academy of Motion Picture Arts and Sciences saw fit to reward her 1999 performance in Girl Interrupted with an Oscar, but I wasn’t well and truly smitten until the second Lara Croft Tomb Raider movie was released in 2003.  In that film, Jolie, who performs her own stunts, is seen ...

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The patient was hacking sputum into a tissue when the resident and I entered his room. “How long have you had that cough?” “Oh this? As long as I can remember.” “But it’s been worse lately?” “Yeah.” “Worse how?” “More stuff coming out each time. See?” He opens the tissue. “How much sputum is there?” “Sputum?” “The stuff you cough up.” “I don’t look that close.” “More than two spoonfuls?” “Oh yes. Definitely.” “And the color?” “White-ish.” “Ever see any streaks of blood?” “Never.” “And how long have ...

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medpagetodayFrom MedPage Today:

  1. Healthier Americans Mean a Stronger Economy. More health insurance results in more Americans who are in better health, which in turn makes the economy stronger.
  2. Dronedarone in Middle Age Linked to More Admissions. Treatment with dronedarone (Multaq) was associated with a higher risk for hospitalization than treatment with amiodarone ...

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medpagetodayFrom MedPage Today:

  1. Brain Cancer: Did '60 Minutes' Report Raise False Hope? A glioblastoma therapy touted in a "60 Minutes" report that aired Sunday evening, focusing on the use of the polio virus to treat glioblastoma, isn’t a particularly new idea and results are still unpublished -- but some oncologists are worried that patients ...

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medpagetodayFrom MedPage Today:

  1. Nephrologists Iffy About Dialysis in Expectant Moms. A third of nephrologists reported being somewhat to very uncomfortable caring for a pregnant patient on hemodialysis despite a growing number having to do so.
  2. What Makes an Opioid Stronger or Weaker Than Morphine? A February 2015 report from the Centers for ...

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At age 37, after a nearly 2-year battle with stage IV lung cancer, a talented neurosurgeon lost his battle. My oncology-related newsfeed is filled with stories this week about this brave and clever man’s recent passing. In a field where the recent tweets tout results of the latest clinical trials (overall survival prolonged from 2 months to 4 months!), it is sobering to be reminded of what truly matters to ...

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