An excerpt from What Is It and How Did I Get It? Early Stage Chronic Kidney Disease. The symptoms of kidney disease don’t show up until you’ve lost most of your kidney function. That’s when you’ll experience the fatigue that’s not always a result of anemia, the muscle cramps that usually - but not always - present themselves in your calves, nausea, vomiting, appetite loss, easy bruising, itching and the shortness of ...

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