Hydroxycut causes liver damage, and why we need to regulate supplements

The popular weight-loss supplement, Hydroxycut, has been recalled.

A 19-year old man died, and another needs a liver transplant. MedPage Today reports that these events occurred in 2007, but wasn’t reported to the FDA until two years later. In all, 23 events were reported, ranging from the aforementioned serious side effects, to elevations in the liver enzyme levels.

Who knows how many more will be affected with the reporting delay? The fact is, “the makers of diet supplements are not required to provide precise ingredient formulae to the FDA.” And without that information, it is impossible to determine what exactly led to the liver complications.

Patients need to be aware that, in some cases, over-the-counter supplements can be more dangerous than prescription drugs.

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  • XMD

    Weight Loss Medicines should only be taken under a doctor’s supervision, whether Over the counter or not. Unfortunately the humans quest for an easy weight loss solution leads to such unfortunate incidents.

  • The Happy Hospitalist

    Um. Any idea how many people die every year from warfarin, when used as directed? How about NSAIDS. Lasix? ACEi? The list is endless regarding the toxic side effects of both over the counter and prescription drugs, even when used as directed.

    Remember Phen-Fen? Regulated and still caused disasters.

    How does regulating hydroxycut make it any less likely to cause harm. If we are going to remove all drugs that cause harm, regulated or not, then we will have to remove all drugs.

  • Anonymous

    It will cost substantially more if it's regulated by the FDA. The FDA has to hire additional scientists, doctors, etc. to supervise. In addition, the manufacturer will need to conduct animal & people trials. All this will get passed onto the consumer, and then there will no longer be any OTC supplements and everything will be by prescription only.

    Mostly likely, the reason supplements are not regulated by the FDA is that there is no incentive (fee) to do so.

  • stargirl65

    A friend of mine has a daughter in her senior year in college. She has been taking hydroxycut. She now needs a liver transplant. If this had been reported earlier then maybe she would be OK.

    Yes, I realize that we cannot remove all dangerous drugs from the market, but people should be informed of the risks. For coumadin and others the risks are known and weighed against the benefits. This does not happen with these otc herbal medicines. It is not the same.

  • Christian Molstrom

    The purpose of regulation is not to remove harmful drugs from the market, it is to control access to them depending on risks, and provide information about risks so that consumers can make informed decisions. Those are all good things. It also adds some protection from liability, which hydroxycut will most certainly be facing.

    I don’t know how rigorous the effectiveness and risk studies should be for any new product. These things are very expensive to do well. It is always a innovation vs. safety issue. Perhaps there should be mandatory reporting of serious adverse events, like a death, even for herbs/supplements. That would make sense.

  • Anonymous

    Well, if anyone is harmed, there obviously must be more regulation. If we can just get the enough laws in place, no one will ever have to take risks or suffer from their own decisions or from misfortune.

  • Mike

    I posted about hydroxycut in Iraq on my blog 2 yrs ago, but I’ll say it again, the majority of health food supplements DON’T DO ANYTHING!!! So regulation is not the answer. Its education of a gullible public who buys this garbage!! Its a multi BILLION dollar industry… and who’s dollars are they? The same people who go to chiropractors, purchase colon cleanse, visit the cancer treatment center of america, visit “N.D”‘s, and buy Kevin Trudeau’s “books”.

    Ephedra and Hydroxycut were rarely fatal, but the entire industry is just a joke and fleecing America.

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