Wednesday, April 30, 2008

My take: Just say no to unnecessary tests

This is a piece that I wrote awhile back. I have used some of the article's wording in recently published op-eds.

"Aren't you are going to order a urine test, chest x-ray or electrocardiogram?"

The patient before me was a healthy adult I was seeing for a preventive health exam. As a primary care physician, I frequently encounter similar questions. Despite lacking studies suggesting any benefit to ordering these tests in asymptomatic patients, almost half of physicians do so routinely.

Our health care system contains a myriad of incentives encouraging rampant testing. One reason is the doctor's desire to avoid lawsuits by practicing defensive medicine. Additionally, the physician payment system encourages medical excess.

Another factor flies under the radar. It takes a willing patient to partake in the overtesting phenomenon. We need to question why.

The stakes in our health system are high, and the statistics grim. Despite spending almost twice as much per patient compared to other industrialized countries, the United States ranks poorly when it comes health outcomes. Health care expenditures in 2007 totaled $2.3 trillion, and is expected to almost double over the next decade. Excessive testing, combined with the demand for the newest, more expensive diagnostic modalities, play a pivotal role in increasing costs. For instance, acquiescing to this patient's request and indiscriminately ordering routine urine tests, chest x-rays and electrocardiograms in everybody can cost almost $200 million annually.

Patients usually do not consider national health care costs when discussing the need for testing. Perpetuated by the media, the common mentality is that "more tests must mean better medicine". Gary Schwitzer, Associate Professor at the University of Minnesota's School of Journalism, leads a team that evaluates and grades health stories in the news. Regarding the media, he notes a "surprisingly strong evidence of bias" in favor of tests. Even respected health journalists and television physician personalities occasionally ignore rigorously studied clinical medicine guidelines. Explaining evidence does not lend itself to sound bites, which often diminishes discussing the risks of a diagnostic test.

Every test has the possibility of a "false positive", defined as a positive result in the absence of disease. A relatively accurate study like a mammogram has a false positive rate of 5 percent. Contrast this to a urine test screening for bladder cancer, which at 35 percent, has a significantly higher false positive rate. False positives lead to progressively more invasive tests - like a needle biopsy or CT scan - where the complications become more dangerous. Consider that a needle biopsy can lead to significant bleeding and infection, and a single CT scan exposes the patient to potentially cancer-causing radiation equivalent to 400 chest x-rays.

Granted, many tests are beneficial. Screening studies looking for abnormal cholesterol levels, colon cancer, breast cancer and cervical cancer have been shown to save lives. If a patient has a concerning symptom, obtaining the appropriate test is imperative. However, subjecting the healthy population to unproven tests does not necessarily yield better results. In fact, data suggests that more intensive medical care can be associated with worse outcomes coupled with an increasing degree of medical errors and cost.

The public should be pro-active addressing the complications of medical procedures and imaging scans, especially if their doctors don't. Studies have shown that patients tend to decline tests of questionable benefit when they are aware of the true risks. Understand that there is pro-testing bias in the media. Anecdotes of catching disease impact emotionally on TV and sell newspapers. Explaining medical evidence doesn't inherently have a "human side", and is subsequently downplayed. Health stories should be critically analyzed before being believed.

Back to my patient, who is waiting for an answer. Major guidelines recommend against ordering a routine urine test, chest x-ray, or electrocardiogram for the screening of bladder cancer, lung cancer, and heart disease respectively. There are no studies suggesting any improvement in patient outcomes by ordering these tests in the asymptomatic patient.

The answer is clear.

We need to say no to unnecessary tests.


Comments:
There's so MUCH grey area with regard to screening tests, however. It's one thing to say don't screen the "herd" of asymptomatic patients routinely for bladder cancer, or lung cancer, or irregular cardiac activity.

But what about the individual patient...the one who might have no symptoms, but who has special risk factors for developing any or all of the above?

A smoker, or person with exposure to bladder carcinogens, with close family member who have had bladder cancer...is it outrageous to test when risk is higher than the mean of the herd?
How about a person who is or was a very heavy smoker, for a long term, or has other risk factors...but is essentially asymptomatic but for morning cough? And so on.

The picture is even fuzzier when such a patient has vague or common symptoms. Should what applies to a healthy "herd" apply to that individual?

It's unfortunate but doctors will justify refusing testing because most people won't be sick at all...and individuals who really don't have the same risk level, will be treated like an average member of the herd.
 
That's what your annual health maintenance visit is for- reviewing your past, family and social history to see how your individual risk varies from others of your age and gender and then discussing how the population recommendations might apply to you.

The actual "annual physical exam" is the least valuable part of this annual visit.
 
It's a pretty good post It is refreshing to hear a doctor suggest to us to say "no" - it makes us realize that at least some doctors don't mind us doing it.

One thing that I think the post doesn't consider is the actual difficulty a patient may have in saying "no" to a doctor as well as lack of knowledge of most patients.

Most patients have no way to know if a test is necessary or not. Sure, there are some who want every test they see on TV mistakenly thinking that it is necessary. But I'd suspect, the majority simply follow doctor's suggestions. How can an average patient who is asked to do a urine test, for example, is supposed to know if it is necessary or not? For many people - if my doctor orders it, then it is necessary.

Additionally, a doctor is a figure or authority. A doctor "knows best". A lot of people, present company included, is very uncomfortable "questioning the doctor's judgement". One is afraid to be considered a "difficult patient" or "non-compliant". Even if a test cost money and part of the deductible - as it often is in my case - it is sometimes emotionally easier to just submit than to argue. At least for me - sometimes I know that a test is no necessary and can even cause more harm, but I don't want to "be difficult". Or if a doctor orders multiple tests, I pick and choose "my battles" - I may refuse one but not the other so that not to "be difficult".

Lastly, refusal takes time. In my experience with annual physicals a non-recommended and, for many patients, unnecessary EKJ is done by a nurse before I even get to see a doctor. Asking a nurse "is it really necessary in my specific case?" and you'll get reply "sure, the doctor ordered it". An unnecessary urine test is just another paper slip a doctor gives you before you leave the office. By that time, your visit is almost over, and, the environment is often not conducive to additional questions.

I stopped going to annual physicals because of that. I think I'll go to one when I am 50 which will be in a year, just so to do colon cancer screening which is one of very few screening tests that I actually think I'll choose to do. Beyond that - I'll go to a doctor when I am sick.
 
It is not uncommon to have a healthy patient request a CA125 to rule out ovarian cancer, like killed Golda Radner. I do not refuse but I give the patient an idea about the risk/benefit ratio, the uncertain screening interval and the population studies that show no benenfit. I also tellher that the possibility of a false positive is as high as 30% and that if she does have an elevated level, even with no other finding, I am pretty much obligated to do a laparoscopy and probably a bilateral oophorectomy, which will probably show no disease. None the less, I will get a mortgage payment out of it, or maybe a nice dinner out with my wife depending on the insurance company. So, great, go ahead and make my day!
 
Earlier this month, in one of my posts, I gave a clinical example on how to decide whether or not to do a test based on
1. COST/INCONVENIENCE of the test.
2. LIKELIHOOD of finding something positive
3. USEFULNESS in how much the test results will change your medical decisions.

Many of these screening tests are expensive on a mass basis (especially when taking into account follow-up for false positives), they are unlikely to be abnormal and even if they are abnormal, it's not clear what actions to take to change the actual clinical outcomes.
 
Or, just say yes and improve your income. Patient feels better. You feel better. Your family likes the new boat better. Your defense attorney feels better. The insurance company does not care, they just pass the rates along to the patient. So, why the fuss?
 
200 million? That is nothing! Less than peanuts! That is less than a dollar per person and if that is all it costs, any benefit at all is worth it.

But I don't think that number is anywhere near right. There are clearly some missing zeros.

As long as people pay for their own basic healthcare--screening is not an unexpected catastrophe and is not therefore an insurable event--I don't see why the cost should matter if people want it. I think everyone who isn't indigent should pay for their own.

My objection is that if it isn't medically indicated, then it is contraindicated because of the mischief--sometimes fatalities, that false positives lead to. The last thing I want is some serious complication of an invasive procedure to follow-up a test that I shouldn't have gotten in the first place.

I regret ever checking my cholesterol. Borderline numbers--which mean that, like nearly everyone else, I fall into a category where those who stand to profit from selling statins say I should be on them so I got on them. . . damned near killed me!

Not only did I get off them, I don't check my cholesterol anymore--felt much better when it was high.
 
My doctor only did an EKG when I had an irregular heartbeat. Other than that I only get blood and urine tests each year. Urine doesn't seem to reveal too much....maybe he's checking for glucose (diabetes)? I know despite my youth he does pay particular attention to my cholesterol (probably because of my terrible diet)...but it's always been good.
 
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