<?xml version="1.0" encoding="UTF-8"?><rss version="2.0" xmlns:content="http://purl.org/rss/1.0/modules/content/" xmlns:dc="http://purl.org/dc/elements/1.1/" xmlns:atom="http://www.w3.org/2005/Atom" xmlns:sy="http://purl.org/rss/1.0/modules/syndication/" > <channel><title>Comments on: Tight diabetes guidelines and the &quot;glitazone&quot; problem</title> <atom:link href="http://www.kevinmd.com/blog/2007/09/tight-diabetes-guidelines-and-glitazone.html/feed" rel="self" type="application/rss+xml" /><link>http://www.kevinmd.com/blog/2007/09/tight-diabetes-guidelines-and-glitazone.html</link> <description></description> <lastBuildDate>Wed, 15 Feb 2012 00:27:00 +0000</lastBuildDate> <sy:updatePeriod>hourly</sy:updatePeriod> <sy:updateFrequency>1</sy:updateFrequency> <xhtml:meta xmlns:xhtml="http://www.w3.org/1999/xhtml" name="robots" content="noindex" /> <item><title>By: Christine-Megan</title><link>http://www.kevinmd.com/blog/2007/09/tight-diabetes-guidelines-and-glitazone.html#comment-80005</link> <dc:creator>Christine-Megan</dc:creator> <pubDate>Fri, 14 Sep 2007 01:37:00 +0000</pubDate> <guid isPermaLink="false">http://clients.emmense.com/kevinmd/2007/09/tight-diabetes-guidelines-and-the-glitazone-problem.html#comment-80005</guid> <description>Gah, I couldn&#039;t agree less!  &lt;br/&gt;&lt;br/&gt;Instead of using 3 oral medications and still having sub-optimal results, I think the focus should be on adding insulin sooner.  But I think many physicians don&#039;t want to do this.  And certainly many patients don&#039;t.  So instead we get sub-optimal control leading to heart disease on a drug that leads to heart disease.&lt;br/&gt;&lt;br/&gt;I do NOT think the a1c targets should be lessened.  7% is the ADA&#039;s goal.  The AACE recommends 6.5%.  8% is an average glucose of nearly 210.  Research I&#039;ve seen suggests that damage occurs over 150.  Some feel it happens even lower.&lt;br/&gt;&lt;br/&gt;So maybe we&#039;ll cut the risk of side effects from OA&#039;s, we&#039;ll just kill their kidneys, eyes, and peripheral circulation, and possibly still end up with heart disease.&lt;br/&gt;&lt;br/&gt;Bad plan imho.</description> <content:encoded><![CDATA[<p>Gah, I couldn&#8217;t agree less!</p><p>Instead of using 3 oral medications and still having sub-optimal results, I think the focus should be on adding insulin sooner.  But I think many physicians don&#8217;t want to do this.  And certainly many patients don&#8217;t.  So instead we get sub-optimal control leading to heart disease on a drug that leads to heart disease.</p><p>I do NOT think the a1c targets should be lessened.  7% is the ADA&#8217;s goal.  The AACE recommends 6.5%.  8% is an average glucose of nearly 210.  Research I&#8217;ve seen suggests that damage occurs over 150.  Some feel it happens even lower.</p><p>So maybe we&#8217;ll cut the risk of side effects from OA&#8217;s, we&#8217;ll just kill their kidneys, eyes, and peripheral circulation, and possibly still end up with heart disease.</p><p>Bad plan imho.</p> ]]></content:encoded> </item> </channel> </rss>
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