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	<title>Comments on: </title>
	<atom:link href="http://www.kevinmd.com/blog/2006/02/useful-cancer-drug-where-cost-is.html/feed" rel="self" type="application/rss+xml" />
	<link>http://www.kevinmd.com/blog/2006/02/useful-cancer-drug-where-cost-is.html</link>
	<description>medical blog</description>
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		<title>By: mcp92</title>
		<link>http://www.kevinmd.com/blog/2006/02/useful-cancer-drug-where-cost-is.html/comment-page-1#comment-59382</link>
		<dc:creator>mcp92</dc:creator>
		<pubDate>Fri, 17 Feb 2006 01:57:00 +0000</pubDate>
		<guid isPermaLink="false">http://clients.emmense.com/kevinmd/2006/02/20043.html#comment-59382</guid>
		<description>The dose used for breast and lung cancer is double the dose used for colon cancer.</description>
		<content:encoded><![CDATA[<p>The dose used for breast and lung cancer is double the dose used for colon cancer.</p>
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		<title>By: Anonymous</title>
		<link>http://www.kevinmd.com/blog/2006/02/useful-cancer-drug-where-cost-is.html/comment-page-1#comment-59321</link>
		<dc:creator>Anonymous</dc:creator>
		<pubDate>Wed, 15 Feb 2006 20:59:00 +0000</pubDate>
		<guid isPermaLink="false">http://clients.emmense.com/kevinmd/2006/02/20043.html#comment-59321</guid>
		<description>I&#039;m not a medical oncologist.&lt;br/&gt;&lt;br/&gt;Here&#039;s some data.&lt;br/&gt;&lt;br/&gt;Dosage for Avastin for metastatic colorectal cancer is 5 mg/kg q14 days &quot;until disease progression is detected,&quot; implyng that Avastin is given every two weeks without an end point.  Probably because the patient has metastatic or stage 4 disease.&lt;br/&gt;&lt;br/&gt;For a 165 lb. or 75 kg. patient this works out to 375 mg every 2 weeks or 9,750 mg/year.&lt;br/&gt;&lt;br/&gt;Avastin is packaged in 100 mg vials so this 75 kg. patient would require 98 vials per year.&lt;br/&gt;&lt;br/&gt;The quoted RETAIL price of 98 vials of Avastin at Drugstore.com is $60,638.&lt;br/&gt;&lt;br/&gt;I would assume that Genentech would sell Avastin for a lesser wholesale price.&lt;br/&gt;&lt;br/&gt;So by my calculations, the price of a year of Avastin for metastatic colorectal cancer should be less than half the price in this news story.&lt;br/&gt;&lt;br/&gt;Maybe there&#039;s a different dosage for the off-label use for breast cancer.&lt;br/&gt;&lt;br/&gt;Please correct me if my information is incorrect.</description>
		<content:encoded><![CDATA[<p>I&#8217;m not a medical oncologist.</p>
<p>Here&#8217;s some data.</p>
<p>Dosage for Avastin for metastatic colorectal cancer is 5 mg/kg q14 days &#8220;until disease progression is detected,&#8221; implyng that Avastin is given every two weeks without an end point.  Probably because the patient has metastatic or stage 4 disease.</p>
<p>For a 165 lb. or 75 kg. patient this works out to 375 mg every 2 weeks or 9,750 mg/year.</p>
<p>Avastin is packaged in 100 mg vials so this 75 kg. patient would require 98 vials per year.</p>
<p>The quoted RETAIL price of 98 vials of Avastin at Drugstore.com is $60,638.</p>
<p>I would assume that Genentech would sell Avastin for a lesser wholesale price.</p>
<p>So by my calculations, the price of a year of Avastin for metastatic colorectal cancer should be less than half the price in this news story.</p>
<p>Maybe there&#8217;s a different dosage for the off-label use for breast cancer.</p>
<p>Please correct me if my information is incorrect.</p>
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		<title>By: Anonymous</title>
		<link>http://www.kevinmd.com/blog/2006/02/useful-cancer-drug-where-cost-is.html/comment-page-1#comment-59312</link>
		<dc:creator>Anonymous</dc:creator>
		<pubDate>Wed, 15 Feb 2006 19:10:00 +0000</pubDate>
		<guid isPermaLink="false">http://clients.emmense.com/kevinmd/2006/02/20043.html#comment-59312</guid>
		<description>That doesn&#039;t surprise me they charge me nearly $24,000 a year for my hormone replacement.</description>
		<content:encoded><![CDATA[<p>That doesn&#8217;t surprise me they charge me nearly $24,000 a year for my hormone replacement.</p>
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