Comments on: On prescription drug costs http://www.kevinmd.com/blog/2004/09/on-prescription-drug-costs.html Tue, 14 Feb 2012 17:18:00 +0000 hourly 1 By: Anonymoushttp://www.kevinmd.com/blog/2004/09/on-prescription-drug-costs.html#comment-51666 Anonymous Tue, 21 Sep 2004 22:48:00 +0000 http://clients.emmense.com/kevinmd/2004/09/on-prescription-drug-costs.html#comment-51666 how about the NIH funding Phase IV clinical trials for generic medicines in new indications?<br /><br />seems like a good use of public resources to do what private industry wouldn't (no economic motive). could be very interesting given that many newer drugs have indications that are more "modern" than the generic that they replace. it might be a more targeted patient group, it might be a study in conjunction with newer treatments that are closer to current clinical practice, it might be a different dosing schedule.<br /><br />it could be difficult to give out $50-100 million dollar grants to do this, especially given the failure rate of drugs in phase IV trials (not as bad as phase III failure rates, but not very good)<br /><br />just thinking <br /><br />-jeet how about the NIH funding Phase IV clinical trials for generic medicines in new indications?

seems like a good use of public resources to do what private industry wouldn’t (no economic motive). could be very interesting given that many newer drugs have indications that are more “modern” than the generic that they replace. it might be a more targeted patient group, it might be a study in conjunction with newer treatments that are closer to current clinical practice, it might be a different dosing schedule.

it could be difficult to give out $50-100 million dollar grants to do this, especially given the failure rate of drugs in phase IV trials (not as bad as phase III failure rates, but not very good)

just thinking

-jeet

]]> By: Anonymoushttp://www.kevinmd.com/blog/2004/09/on-prescription-drug-costs.html#comment-51649 Anonymous Fri, 03 Sep 2004 20:09:00 +0000 http://clients.emmense.com/kevinmd/2004/09/on-prescription-drug-costs.html#comment-51649 I think that's a good first step, but even 20-30$ is much cheaper than 100$ per month that many meds cost. I think that’s a good first step, but even 20-30$ is much cheaper than 100$ per month that many meds cost.

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