As you may have heard, the new NCEP cholesterol guidelines were released yesterday. The biggest change is a goal LDL of < 70 in the very high risk group. Now, what classifies as very high risk? They are the following:
Established CAD plus:
i) multiple major risk factors (esp. diabetes)
ii) severe and poorly controlled risk factors (i.e. continued smoking)
iii) multiple risk factors of the metabolic syndrome (esp. triglycerides >200, non-HDL >130 with low HDL <40)
iv) acute coronary syndrome
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- High Cholesterol
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I’m curious what the science is behind this.
Do we have large-scale trials showing these primary and secondary prevention goals meet basic cost-benefit analyses?
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