Tuesday, May 25, 2004
Hiccups
Medpundit wrote about hiccups today. It reminded me about one of my patients who had protracted hiccups for 5 years - you could only imagine how frustrating this was. He was a 70-yo male who started having hiccups after surgery. Multiple medications were not successful: PPIs, H2 blockers, Thorazine, Reglan, Compazine, Neurontin and Dilantin were given without success. Endless GI and neurology consults were not revealing. There were some small studies using Baclofen for the control of hiccups - and this resulted in mild improvement. However, there continued to be breakthrough episodes. I also read some case reports using Amitriptyline to treat intractible hiccups. Currently, with a regimen of Amitriptyline 100mg at night and Baclofen 10mg 3x/day, it seems like they under adequate control so that the patient can resume a normal life.
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I would really like to see more information on how effective neurotin really is for hiccups. My dad is 85 years old. He has been battling the hiccups for about 1 year. Hospitalized several times for this with many consults including GI guys, Neurologist,pulmonalogists, ENT guys, you names it. Let me know if anyone has heard of nefopam given in Italy for a few cases of severe hiccups. I know you cannot get it here in the U.S. Thanks for the article though it's a perplexing problem. Sally
# posted by 
: 8:43 PM
: 8:43 PM
My husband has had hiccups most of every day for 6 plus years. Earlier, he had them for eight months, then they ended for nearly nine years. He, too, has tried Baclofen, Thorazine, GERD-type pills and, most recently, Neurontin. That seemed to ease them a bit, but also seems to wear off. He tries adusting the dosage both upwards and downwards, without significant change in their occurrence.
We wondered about Nefopam and anyone's success with it?
We wondered about Nefopam and anyone's success with it?
# posted by : 1:21 PM
: 1:21 PM
I have had protracted hiccups approximately every three years. They have lasted from 48 hours to 10 days. Thorazine was effective once, but the second time (3 years later) the dosage was increased, resulting in a severe allergic reaction.
Over the past years, my brother has had protracted hiccups on two occassions, lasting from 2 to 3 days each. Has anyone heard of this being a genetic trait?
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Over the past years, my brother has had protracted hiccups on two occassions, lasting from 2 to 3 days each. Has anyone heard of this being a genetic trait?
# posted by : 9:45 PM
: 9:45 PM
